Uses of Titanium Nitride Ceramic Materials in Biomedicine

What does titanium nitride mean?

The typical NaCl structure of titanium nitride is TiN. This is a cubic-shaped face-centred lattice that has an average lattice a=0.4241nm. Titanium atoms are at the corners. TiN can be altered within certain limits without altering the TiN composition. TiN powder is usually yellow-brown. The ultrafine TiN Powder is black. TiN crystals have a golden color. TiN is very resistant to thermal shock, has a melting point of 2950°C, a density of 5.43-5.44g/cm3, Mohs Hardness of 8-9 and a Mohs toughness of 8. TiN has a melting point that is greater than many transition metals nitrides. However, its density is much lower than the most transition metal nitrides. This makes it a highly heat-resistant and distinctive material. TiN has a crystal structure similar to TiC but the C atoms have been replaced by N atoms.

Titanium Nitride Application in Biomedicine

In clinical medicine, the implant has been used extensively as an interventional treatment device. It is used to treat atrial septal defect, patent ductus arteriosus and ventricular septal defect. The majority of concentric occluders made from nickel-titanium alloy materials contain at least 55% nickel. The long-term consequences of excessive nickel exposure can lead to allergies or poisoning in the human body. Surface purification membranes of the nickel-titanium occluder alloy can be damaged. Internal nickel ions released in complex environments of the body may increase nickel content. This will further deteriorate tissue compatibility.

According to relevant studies, titanium nitride is an alloy with excellent biocompatibility. It was previously used as a coronary stent material. The thrombus origin of this metal is therefore much lower that that of nickel-titanium. To address this problem scientists developed Cera ceramic membranes that occlude using high-energy Ion precipitation coating technology. These retain the original atrial and interventricular septal seals, which were based upon the original nickel-titanium occluder. Patent ductus arteriosus and the design of this occluder use plasma technology to uniformly coat a titanium nitride TiN layer on the surface. The metal titanium coating is combined with C, O, and other compounds can be transformed into the biological layer. It dramatically increases the occluder’s resistance to corrosion and allows for the compatibility between biological tissues and blood. The Cera ceramic membrane is superior to ordinary nickel-titanium in terms of cell creeping performance, as evidenced by the animal experiment results. It reduces the risk for congenital heart defects, improves healing times and decreases the likelihood of thrombosis. Platelet adhesion rates and hemolysis are lower than with ordinary nickel-titanium. Cera has currently been approved by Russia, India, Brazil, Russia, and many other countries. The Cera occluder has been approved by the European Union, India, Brazil and Russia for use in congenital heart diseases. TRUNNANO is also known as. Lempotee Nano Technology Co. Ltd. is a reliable global supplier and manufacturer of chemical materials with more than 12 years’ experience in producing super-high quality chemicals and Nanomaterials. Our superfine Titan nitride Powder is of high purity. It has a small particle size, and low impurity. We can help you if your requirements are lower.
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